RTA-3
RTA-3 Triple-Receptor Agonist Peptide
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RTA-3 is a novel triple-receptor agonist peptide consisting of 39 amino acids with a C18 fatty diacid conjugation at Lys20 via a γGlu-2×OEG linker. At 4757.52 Da molecular weight and ≥99% HPLC-verified purity, RTA-3 is designed for research into simultaneous GLP-1, GIP, and glucagon receptor activation. This triple-agonist approach is studied for its potential in metabolic regulation research. Peak Revival Plus supplies RTA-3 as a lyophilized powder for in-vitro research only.
RTA-3 Quick Facts
| Chemical Name | RTA-3 Triple-Receptor Agonist Peptide |
| CAS Number | N/A (Novel Research Compound) |
| Molecular Weight | 4757.52 Da |
| Molecular Formula | C₂₁₂H₃₃₄N₅₈O₆₈ |
| Sequence | 39-amino-acid linear peptide with C18 fatty diacid conjugation at Lys20 via γGlu-2×OEG linker |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder (white) |
| Storage | Store lyophilized at -4°F (-20°C) in a dry, dark environment. Reconstituted solutions should be stored at 36-46°F (2-8°C) and used within 14 days. Avoid repeated freeze-thaw cycles. Protect from light and moisture at all times. |
| Shelf Life | 24 months (sealed, stored at −20 °C) |
| Also Known As | RTA-3 Triple-Receptor Agonist |
What is RTA-3?
RTA-3 is a triple-action synthetic research peptide designed for advanced in vitro investigation of multi-receptor incretin signaling. Comprising a 39-amino-acid sequence with a C18 fatty diacid side chain conjugated at position 20, RTA-3 exhibits simultaneous high-affinity binding at GIP, GLP-1, and glucagon receptor subtypes — making it one of the most versatile tools available for studying tri-agonist receptor pharmacology in controlled laboratory settings. In preclinical cell-based assays, RTA-3 has demonstrated potent and balanced activation across all three target receptors, with nanomolar-to-picomolar EC50 values depending on the receptor subtype and assay conditions. This tri-receptor engagement profile makes RTA-3 particularly valuable for researchers investigating synergistic metabolic signaling, energy expenditure pathways, hepatic glucose output regulation, and adipose tissue lipolysis mechanisms. Each vial contains 10 mg of lyophilized RTA-3 at ≥99% purity (verified by HPLC and mass spectrometry). The lyophilized powder is formulated for reconstitution in bacteriostatic water or sterile saline prior to use in research protocols. Peak Revival Plus manufactures RTA-3 under strict GMP-adjacent laboratory conditions with full certificate of analysis (COA) provided with every order. This product is intended for laboratory research use only. Not for human consumption, veterinary use, or diagnostic purposes.
What are the research applications of RTA-3?
Triple incretin receptor binding studies, GIP/GLP-1/glucagon signaling pathway analysis, synergistic metabolic signaling research, energy expenditure pathway modeling, hepatic glucose output regulation studies, adipose tissue lipolysis mechanism research, tri-agonist pharmacology characterization, dose-response profiling
How should RTA-3 be stored?
Store lyophilized at -4°F (-20°C) in a dry, dark environment. Reconstituted solutions should be stored at 36-46°F (2-8°C) and used within 14 days. Avoid repeated freeze-thaw cycles. Protect from light and moisture at all times.
Quality Certifications
All products meet strict purity standards
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Third-party lab testing for accuracy
Manufactured following WHO guidelines
View Certificate of Analysis (COA)
Every batch is independently tested by third-party laboratories. View the verified COA for RTA-3 with purity data, HPLC chromatogram, and mass spectrometry results.
Frequently Asked Questions
Common questions about RTA-3 (RTA-3 Triple-Receptor Agonist Peptide). Can't find what you're looking for? Contact our research support team.
Every batch is independently tested by accredited third-party laboratories with full Certificates of Analysis (COA) available on request. We guarantee ≥98% purity across our catalog, use pharmaceutical-grade lyophilization, and ship with cold-chain packaging to preserve compound integrity. Our research-grade peptides are manufactured under strict GMP-compliant conditions, ensuring consistency and reliability that many competitors cannot match.
Yes. We can provide HPLC, mass spectrometry, endotoxin testing, and amino acid analysis reports for any product. If you need a specific assay or custom testing protocol for your research, contact us at [email protected] and we will coordinate with our laboratory partners to accommodate your requirements.
Absolutely. We offer tiered pricing for research institutions, universities, and laboratories ordering in volume. Discounts typically start at 10+ units and scale with quantity. Contact us at [email protected] with your institutional details and estimated quantities for a custom quote. We also support purchase orders (PO) for qualifying institutions.
All orders ship free with same-day processing (orders placed by 12 PM PST). Packages are sent via USPS Priority or UPS Ground with temperature-controlled packaging. Lyophilized peptides are shipped with cold packs to maintain stability. Domestic orders typically arrive within 2–3 business days. Tracking information is provided via email as soon as your order ships.
Due to the nature of research chemicals, we cannot accept returns on opened products. However, if your order arrives damaged, contaminated, or does not meet the stated purity specifications, we will replace it or issue a full refund. Please contact support within 48 hours of delivery with photos of any issues.
No. All products sold by Peak Revival Plus are strictly for in-vitro research and laboratory use only. They are not intended for human consumption, veterinary use, or any therapeutic application. By purchasing, you confirm that you understand and agree to these terms.
What Our Customers Say
Verified feedback from researchers and laboratories across the country
"Exceptional purity and consistency across batches. The COA documentation is thorough and matches our internal HPLC analysis. We've been ordering for our cellular signaling studies for over a year now."
Principal Investigator
"Fast shipping and excellent packaging. Products arrived in perfect condition with proper cold chain maintenance. The purity levels consistently meet or exceed stated specifications."
Lab Manager
"We've tested multiple suppliers and Peak Revival Plus offers the best combination of quality and documentation. Their BPC-157 showed excellent results in our in-vitro wound healing assays."
Research Scientist
"As a grad student, I appreciate the detailed product information and responsive customer service. They answered all my questions about storage and reconstitution protocols."
Graduate Researcher